Methadone is contraindicated in patients with a known hypersensitivity to methadone hydrochloride or any other ingredient rein methadone hydrochloride tablets.
Methadone should Beryllium given with caution and the initial dose reduced hinein certain patients, such as the elderly and debilitated and those with severe impairment of hepatic or renal function, hypothyroidism, Addison's disease, prostatic hypertrophy, or urethral stricture.
Pregnancy and neonatal opioid withdrawal syndrome warning: Children Weltgesundheitsorganisation are born to mothers World health organization used this drug for a long time during pregnancy are at risk of neonatal withdrawal syndrome. This can Beryllium life threatening to the child.
Orthostatic hypotension (low blood pressure when getting up after sitting or lying down). Symptoms can include:
In the selection of an initial dose of methadone hydrochloride tablets, attention should be given to the following:
Since methadone is lipophilic, it has been known to persist hinein the liver and other tissues. The slow release from the liver and other tissues may prolong the duration of methadone action despite low plasma concentrations.
This does not preclude the maintenance treatment of a patient with concurrent opioid addiction who is hospitalized for conditions other than opioid addiction and Weltgesundheitsorganisation requires temporary maintenance during the critical period of his/her stay, or of a patient whose enrollment has been verified rein a program which has been certified for maintenance treatment with methadone.
These characteristics can contribute to cases of iatrogenic overdose, particularly during treatment initiation and dose titration.
Abrupt opioid discontinuation can lead to development of opioid withdrawal symptoms (Teich PRECAUTIONS). Presentation of these symptoms have been associated with an increased risk of susceptible patients to relapse to illicit drug use and should Beryllium considered when assessing the risks and benefit of methadone use.
These can be symptoms that you have taken too much (overdose of) methadone hydrochloride tablets, Methadontabletten online kaufen or the dose is too high for you. They can also be symptoms of a serious heart reaction. These symptoms can lead to serious problems or death if not treated right away.
These side effects include slowed breathing and sedation. Talk to your doctor if you breastfeed your child. You may need to decide whether to stop breastfeeding or stop taking this medication.
For people with seizures: This drug may cause more seizures rein people with epilepsy. If your seizure control gets worse while taking this drug, call your doctor.
Patients seeking to discontinue methadone maintenance treatment of opioid dependence should Beryllium apprised of the high risk of relapse to illicit drug use associated with discontinuation of methadone maintenance treatment.
For children: The safety and effectiveness of this drug haven’t been established in children. It shouldn’t Beryllium used rein children younger than 18 years. Children Weltgesundheitsorganisation accidentally take this drug have a high risk of death from overdosing.